Genetic and Transcriptomic Basis of Intestinal Epithelial Barrier Dysfunction in Inflammatory Bowel Disease

BACKGROUND: Intestinal barrier defects are common in patients with inflammatory bowel disease (IBD). To identify which components could underlie these changes, we performed an in-depth analysis of epithelial barrier genes in IBD. METHODS: A set of 128 intestinal barrier genes was selected. Polygenic...

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Detalhes bibliográficos
Publicado no:Inflamm Bowel Dis
Main Authors: Vancamelbeke, Maaike, Vanuytsel, Tim, Farré, Ricard, Verstockt, Sare, Ferrante, Marc, Van Assche, Gert, Rutgeerts, Paul, Schuit, Frans, Vermeire, Séverine, Arijs, Ingrid, Cleynen, Isabelle
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461205/
https://ncbi.nlm.nih.gov/pubmed/28885228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MIB.0000000000001246
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