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Mitigating the effects of reference sequence bias in single-multiplex massively parallel sequencing of the mitochondrial DNA control region

Sequence analysis of the mitochondrial DNA (mtDNA) control region can provide forensically useful information, particularly in challenging samples where autosomal DNA profiling fails. Sub-division of the 1122-bp region into shorter PCR fragments improves data recovery, and such fragments can be anal...

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Détails bibliographiques
Publié dans:Forensic Sci Int Genet
Auteurs principaux: Huszar, Tunde I., Wetton, Jon H., Jobling, Mark A.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461131/
https://ncbi.nlm.nih.gov/pubmed/30682697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fsigen.2019.01.008
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