Target site antibiotic concentrations in orthopedic/trauma extremity surgery: is prophylactic cefazolin adequately dosed? A systematic review and meta-analysis

Background and purpose — The incidence of surgical site infections (SSIs) in trauma/orthopedic surgery varies between different body parts. Antibiotic prophylaxis (e.g., with cefazolin) lowers infection rates in closed fracture surgery and in primary arthroplasty. For prophylactic antibiotics to pre...

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Vydáno v:Acta Orthop
Hlavní autoři: Sanders, Fay R K, Goslings, J Carel, Mathôt, Ron A A, Schepers, Tim
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461090/
https://ncbi.nlm.nih.gov/pubmed/30739547
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/17453674.2019.1577014
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