Schizophrenia Polygenic Risk Score as a Predictor of Antipsychotic Efficacy in First Episode Psychosis

OBJECTIVE: Pharmacogenomic studies of antipsychotics have typically examined effects of individual polymorphisms; by contrast, polygenic risk scores (PRS) derived from genome-wide association studies (GWAS) can quantify the influence of thousands of common alleles of small effect in a single measure...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Am J Psychiatry
Main Authors: Zhang, Jian-Ping, Robinson, Delbert, Yu, Jin, Gallego, Juan, Wolfgang Fleischhacker, W., Kahn, Rene S., Crespo-Facorro, Benedicto, Vazquez-Bourgon, Javier, Kane, John M., Malhotra, Anil K., Lencz, Todd
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6461047/
https://ncbi.nlm.nih.gov/pubmed/30392411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1176/appi.ajp.2018.17121363
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki