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Identification of α-glucosidase inhibitors from Clinacanthus nutans leaf extract using liquid chromatography-mass spectrometry-based metabolomics and protein-ligand interaction with molecular docking

The present study used in vitro and in silico techniques, as well as the metabolomics approach to characterise α-glucosidase inhibitors from different fractions of Clinacanthus nutans. C. nutans is a medicinal plant belonging to the Acanthaceae family, and is traditionally used to treat diabetes in...

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Detalhes bibliográficos
Publicado no:J Pharm Anal
Main Authors: Murugesu, Suganya, Ibrahim, Zalikha, Ahmed, Qamar Uddin, Uzir, Bisha Fathamah, Nik Yusoff, Nik Idris, Perumal, Vikneswari, Abas, Faridah, Shaari, Khozirah, Khatib, Alfi
Formato: Artigo
Idioma:Inglês
Publicado em: Xi'an Jiaotong University 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6460329/
https://ncbi.nlm.nih.gov/pubmed/31011465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpha.2018.11.001
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