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Adaptively Weighted and Robust Mathematical Programming for the Discovery of Driver Gene Sets in Cancers

High coverage and mutual exclusivity (HCME), which are considered two combinatorial properties of mutations in a collection of driver genes in cancers, have been used to develop mathematical programming models for distinguishing cancer driver gene sets. In this paper, we summarize a weak HCME patter...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Xu, Xiaolu, Qin, Pan, Gu, Hong, Wang, Jia, Wang, Yang
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459865/
https://ncbi.nlm.nih.gov/pubmed/30976053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42500-7
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