Silencing UBE4B induces nasopharyngeal carcinoma apoptosis through the activation of caspase3 and p53

AIM: The human ubiquitination factor E4B (UBE4B) gene is frequently amplified in some solid cancers. However, the role of UBE4B in nasopharyngeal carcinoma (NPC) has not yet been investigated. METHODS: Firstly, we analyzed the expression of UBE4B in NPC samples using real-time quantitative PCR and W...

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Publicat a:Onco Targets Ther
Autors principals: Weng, Chengyin, Chen, Yong, Wu, Yong, Liu, Xia, Mao, Haibo, Fang, Xisheng, Li, Baoxiu, Wang, Lina, Guan, Mingmei, Liu, Guolong, Lu, Lin, Yuan, Yawei
Format: Artigo
Idioma:Inglês
Publicat: Dove Medical Press 2019
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459139/
https://ncbi.nlm.nih.gov/pubmed/31040698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S196132
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