Prophylactic Cranial Irradiation vs Observation in Patients With Locally Advanced Non–Small Cell Lung Cancer: A Long-term Update of the NRG Oncology/RTOG 0214 Phase 3 Randomized Clinical Trial

IMPORTANCE: Brain metastasis (BM) rates are high in locally advanced non–small cell lung cancer (LA-NSCLC), approaching rates seen in small cell lung cancer, where prophylactic cranial irradiation (PCI) is standard of care. Although PCI decreases the incidence of BM in LA-NSCLC, a survival advantage...

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Detalhes bibliográficos
Publicado no:JAMA Oncol
Main Authors: Sun, Alexander, Hu, Chen, Wong, Stuart J., Gore, Elizabeth, Videtic, Gregory, Dutta, Swati, Suntharalingam, Mohan, Chen, Yuhchyau, Gaspar, Laurie E., Choy, Hak
Formato: Artigo
Idioma:Inglês
Publicado em: American Medical Association 2019
Assuntos:
Original Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459052/
https://ncbi.nlm.nih.gov/pubmed/30869743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaoncol.2018.7220
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