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A potential therapy for chordoma via antibody-dependent cell-mediated cytotoxicity (ADCC) employing NK or high affinity NK (haNK) cells in combination with cetuximab

OBJECTIVE: Chordoma is a rare bone tumor derived from the notochord, and is resistant to conventional therapies such as chemotherapy, radiotherapy, and targeting therapeutics. Expression of epidermal growth factor receptor (EGFR) in a large proportion of chordoma specimens indicates that chordoma ma...

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Bibliografske podrobnosti
izdano v:J Neurosurg
Main Authors: Fujii, Rika, Schlom, Jeffrey, Hodge, James W.
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6459012/
https://ncbi.nlm.nih.gov/pubmed/28753113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3171/2017.1.JNS162610
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