Myelin Breakdown in Human Huntington’s Disease: Multi-Modal Evidence from Diffusion MRI and Quantitative Magnetization Transfer

Huntington’s disease (HD) leads to white matter (WM) degeneration that may be due to an early breakdown in axon myelination but in vivo imaging correlates of demyelination remain relatively unexplored in HD compared to other neurodegenerative diseases. This study investigated HD-related effects on a...

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Опубликовано в: :Neuroscience
Главные авторы: Bourbon-Teles, José, Bells, Sonya, Jones, Derek K., Coulthard, Elizabeth, Rosser, Anne, Metzler-Baddeley, Claudia
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier Science 2019
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458992/
https://ncbi.nlm.nih.gov/pubmed/28579146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2017.05.042
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