Enzalutamide versus flutamide for castration-resistant prostate cancer after combined androgen blockade therapy with bicalutamide: study protocol for a multicenter randomized phase II trial (the OCUU-CRPC study)

BACKGROUND: Enzalutamide is an oral androgen receptor targeted agent that has been shown to improve survival in PREVAIL trials and has been approved for patients with chemo-naïve metastatic castration-resistant prostate cancer (CRPC). Meanwhile, flutamide is a non-steroidal oral anti-androgen that w...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Cancer
Main Authors: Iguchi, Taro, Tamada, Satoshi, Kato, Minoru, Yasuda, Sayaka, Yamasaki, Takeshi, Nakatani, Tatsuya
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Study Protocol
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458677/
https://ncbi.nlm.nih.gov/pubmed/30971225
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5526-3
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