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Key Functions and Therapeutic Prospects of Nur77 in Inflammation Related Lung Diseases
The transcription factor Nur77 belongs to the NR4A subfamily of nuclear hormone receptors. It features an atypical ligand-binding site that precludes canonical ligand binding, leading to the designation orphan nuclear receptor. However, recent studies show that small molecules can interact with the...
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| Veröffentlicht in: | Am J Pathol |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Investigative Pathology
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6458520/ https://ncbi.nlm.nih.gov/pubmed/30414411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.10.002 |
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