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Key Functions and Therapeutic Prospects of Nur77 in Inflammation Related Lung Diseases

The transcription factor Nur77 belongs to the NR4A subfamily of nuclear hormone receptors. It features an atypical ligand-binding site that precludes canonical ligand binding, leading to the designation orphan nuclear receptor. However, recent studies show that small molecules can interact with the...

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Detalhes bibliográficos
Publicado no:Am J Pathol
Main Authors: Banno, Asoka, Lakshmi, Sowmya P., Reddy, Aravind T., Kim, Seong C., Reddy, Raju C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458520/
https://ncbi.nlm.nih.gov/pubmed/30414411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2018.10.002
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