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Identifying Critical State of Complex Diseases by Single-Sample-Based Hidden Markov Model

The progression of complex diseases is generally divided as a normal state, a pre-disease state or tipping point, and a disease state. Developing individual-specific method that can identify the pre-disease state just before a catastrophic deterioration, is critical for patients with complex disease...

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Detalhes bibliográficos
Publicado no:Front Genet
Main Authors: Liu, Rui, Zhong, Jiayuan, Yu, Xiangtian, Li, Yongjun, Chen, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458292/
https://ncbi.nlm.nih.gov/pubmed/31019526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00285
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