The Role of Pre-existing Cross-Reactive Central Memory CD4 T-Cells in Vaccination With Previously Unseen Influenza Strains

Influenza vaccination is a common approach to prevent seasonal and pandemic influenza. Pre-existing antibodies against close viral strains might impair antibody formation against previously unseen strains–a process called original antigenic sin. The role of this pre-existing cellular immunity in thi...

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Udgivet i:Front Immunol
Main Authors: Nienen, Mikalai, Stervbo, Ulrik, Mölder, Felix, Kaliszczyk, Sviatlana, Kuchenbecker, Leon, Gayova, Ludmila, Schweiger, Brunhilde, Jürchott, Karsten, Hecht, Jochen, Neumann, Avidan U., Rahmann, Sven, Westhoff, Timm, Reinke, Petra, Thiel, Andreas, Babel, Nina
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458262/
https://ncbi.nlm.nih.gov/pubmed/31019503
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00593
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