Neural anti-inflammatory action mediated by two types of acetylcholine receptors in the small intestine

Gastrointestinal prokinetic agents function as serotonin-4 receptor (5-HT(4)R) agonists to activate myenteric plexus neurons to release acetylcholine (ACh), which then induce anti-inflammatory action. Details of this pathway, however, remain unknown. The aim of this study is to clarify the anti-infl...

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Udgivet i:Sci Rep
Main Authors: Kimura, Hitomi, Imura, Yu-ki, Tomiyasu, Hirotaka, Mihara, Taiki, Kaji, Noriyuki, Ohno, Koichi, Unno, Toshihiro, Tanahashi, Yasuyuki, Jan, Tong-Rong, Tsubone, Hirokazu, Ozaki, Hiroshi, Hori, Masatoshi
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458176/
https://ncbi.nlm.nih.gov/pubmed/30971711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41698-w
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