Inhibition of Pseudomonas aeruginosa and Mycobacterium tuberculosis disulfide bond forming enzymes

In bacteria, disulfide bonds confer stability on many proteins exported to the cell envelope or beyond, including bacterial virulence factors. Thus, proteins involved in disulfide bond formation represent good targets for the development of inhibitors that can act as antibiotics or anti-virulence ag...

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Pubblicato in:Mol Microbiol
Autori principali: Landeta, Cristina, McPartland, Laura, Tran, Ngoc Q., Meehan, Brian M., Zhang, Yifan, Tanweer, Zaidi, Wakabayashi, Shoko, Rock, Jeremy, Kim, Taehyun, Balasubramanian, Deepak, Audette, Rebecca, Toosky, Melody, Pinkham, Jessica, Rubin, Eric J., Lory, Stephen, Pier, Gerald, Boyd, Dana, Beckwith, Jon
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6458069/
https://ncbi.nlm.nih.gov/pubmed/30556355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.14185
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