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Dysferlin-deficiency has greater impact on function of slow muscles, compared with fast, in aged BLAJ mice

Dysferlinopathies are a form of muscular dystrophy caused by gene mutations resulting in deficiency of the protein dysferlin. Symptoms manifest later in life in a muscle specific manner, although the pathomechanism is not well understood. This study compared the impact of dysferlin-deficiency on in...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Lloyd, Erin M., Xu, Hongyang, Murphy, Robyn M., Grounds, Miranda D., Pinniger, Gavin J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457631/
https://ncbi.nlm.nih.gov/pubmed/30970035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0214908
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