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Matrix modification for enhancing the transport properties of the human cartilage endplate to improve disc nutrition
Poor solute transport through the cartilage endplate (CEP) impairs disc nutrition and could be a key factor that limits the success of intradiscal biologic therapies. Here we demonstrate that treating the CEP with matrix metalloproteinase-8 (MMP-8) reduces the matrix constituents that impede solute...
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| Опубликовано в: : | PLoS One |
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| Главные авторы: | , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2019
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6457523/ https://ncbi.nlm.nih.gov/pubmed/30970007 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0215218 |
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