Detecting potential pleiotropy across cardiovascular and neurological diseases using univariate, bivariate, and multivariate methods on 43,870 individuals from the eMERGE network

The link between cardiovascular diseases and neurological disorders has been widely observed in the aging population. Disease prevention and treatment rely on understanding the potential genetic nexus of multiple diseases in these categories. In this study, we were interested in detecting pleiotropy...

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發表在:Pac Symp Biocomput
Main Authors: Zhang, Xinyuan, Veturi, Yogasudha, Verma, Shefali, Bone, William, Verma, Anurag, Lucas, Anastasia, Hebbring, Scott, Denny, Joshua C., Stanaway, Ian B., Jarvik, Gail P., Crosslin, David, Larson, Eric B., Rasmussen-Torvik, Laura, Pendergrass, Sarah A., Smoller, Jordan W., Hakonarson, Hakon, Sleiman, Patrick, Weng, Chunhua, Fasel, David, Wei, Wei-Qi, Kullo, Iftikhar, Schaid, Daniel, Chung, Wendy K., Ritchie, Marylyn D.
格式: Artigo
語言:Inglês
出版: 2019
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457436/
https://ncbi.nlm.nih.gov/pubmed/30864329
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