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Experimentally reduced insulin/IGF‐1 signaling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring

Classical theory maintains that ageing evolves via energy trade‐offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new theory postulates that ageing evolves because of deleterious late‐life hyper‐function of reproduction‐p...

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Detalles Bibliográficos
Publicado en:Evol Lett
Autores principales: Lind, Martin I., Ravindran, Sanjana, Sekajova, Zuzana, Carlsson, Hanne, Hinas, Andrea, Maklakov, Alexei A.
Formato: Artigo
Lenguaje:Inglês
Publicado: John Wiley and Sons Inc. 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457396/
https://ncbi.nlm.nih.gov/pubmed/31007945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/evl3.108
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