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Experimentally reduced insulin/IGF‐1 signaling in adulthood extends lifespan of parents and improves Darwinian fitness of their offspring

Classical theory maintains that ageing evolves via energy trade‐offs between reproduction and survival leading to accumulation of unrepaired cellular damage with age. In contrast, the emerging new theory postulates that ageing evolves because of deleterious late‐life hyper‐function of reproduction‐p...

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Dades bibliogràfiques
Publicat a:Evol Lett
Autors principals: Lind, Martin I., Ravindran, Sanjana, Sekajova, Zuzana, Carlsson, Hanne, Hinas, Andrea, Maklakov, Alexei A.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457396/
https://ncbi.nlm.nih.gov/pubmed/31007945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/evl3.108
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