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Sex-related dimorphism in dentate gyrus atrophy and behavioral phenotypes in an inducible tTa:APPsi transgenic model of Alzheimer’s disease

Sex differences are a well-known phenomenon in Alzheimer’s disease (AD), with women having a higher risk for AD than men. Many AD mouse models display a similar sex-dependent pattern, with females showing earlier cognitive deficits and more severe neuropathology than males. However, whether those di...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Neurobiol Dis
Hauptverfasser: Melnikova, Tatiana, Park, DaMin, Becker, Lauren, Lee, Deidre, Cho, Eugenia, Sayyida, Nuzhat, Tian, Jing, Bandeen-Roche, Karen, Borchelt, David R., Savonenko, Alena V.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2016
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457346/
https://ncbi.nlm.nih.gov/pubmed/27569580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2016.08.009
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