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Activated Mesenchymal Stromal Cells Process and Present Antigens Regulating Adaptive Immunity

Mesenchymal stromal cells (MSCs) are inherently immunomodulatory through production of inhibiting soluble factors and expression of immunosuppressive cell surface markers. We tested whether activated MSCs qualify for the induction of antigen-specific immune regulation. Bone marrow derived human MSCs...

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Veröffentlicht in:Front Immunol
Hauptverfasser: van Megen, Kayleigh M., van 't Wout, Ernst-Jan T., Lages Motta, Julia, Dekker, Bernice, Nikolic, Tatjana, Roep, Bart O.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457321/
https://ncbi.nlm.nih.gov/pubmed/31001285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00694
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