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Galantamine-memantine combination superior to donepezil-memantine combination in Alzheimer’s disease: critical dissection with an emphasis on kynurenic acid and mismatch negativity

BACKGROUND: The donepezil-memantine combination is a US Food and Drug Administration (FDA)–approved medication to treat Alzheimer’s disease (AD). Galantamine is superior to donepezil because it is a positive allosteric modulator of the alpha-7 nicotinic acetylcholine receptor (α7nAChR). Although gal...

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Detalhes bibliográficos
Publicado no:J Geriatr Care Res
Main Authors: Koola, Maju Mathew, Nikiforuk, Agnieszka, Pillai, Anilkumar, Parsaik, Ajay K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457262/
https://ncbi.nlm.nih.gov/pubmed/30984874
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