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Smooth muscle cell-specific knockout of neuropilin-1 impairs postnatal lung development and pathological vascular smooth muscle cell accumulation

Neuropilin 1 (NRP1) is important for neuronal and cardiovascular development due to its role in conveying class 3 semaphorin and vascular endothelial growth factor signaling, respectively. NRP1 is expressed in smooth muscle cells (SMCs) and mediates their migration and proliferation in cell culture...

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Bibliografiske detaljer
Udgivet i:Am J Physiol Cell Physiol
Main Authors: Mahmoud, Marwa, Evans, Ian M., Mehta, Vedanta, Pellet-Many, Caroline, Paliashvili, Ketevan, Zachary, Ian
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457104/
https://ncbi.nlm.nih.gov/pubmed/30649916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00405.2018
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