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Altered skeletal muscle microtubule-mitochondrial VDAC2 binding is related to bioenergetic impairments after paclitaxel but not vinblastine chemotherapies

Microtubule-targeting chemotherapies are linked to impaired cellular metabolism, which may contribute to skeletal muscle dysfunction. However, the mechanisms by which metabolic homeostasis is perturbed remains unknown. Tubulin, the fundamental unit of microtubules, has been implicated in the regulat...

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Detalles Bibliográficos
Publicado en:Am J Physiol Cell Physiol
Autores principales: Ramos, Sofhia V., Hughes, Meghan C., Perry, Christopher G. R.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6457100/
https://ncbi.nlm.nih.gov/pubmed/30624982
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00384.2018
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