HDAC3-Selective Inhibition Activates Brown and Beige Fat Through PRDM16

It has been reported that class I histone deacetylase (HDAC) inhibition increases thermogenesis in fat, but adipocyte-specific Hdac3 deletions have presented inconsistent results. In this study, we observed that HDAC3 protein levels were lower in brown fat compared with inguinal subcutaneous adipose...

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Bibliographische Detailangaben
Veröffentlicht in:Endocrinology
Hauptverfasser: Liao, Jiling, Jiang, Juan, Jun, Heejin, Qiao, Xiaona, Emont, Margo P, Kim, Dong-il, Wu, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Endocrine Society 2018
Schlagworte:
Brief Report
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456926/
https://ncbi.nlm.nih.gov/pubmed/29757434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00257
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