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α7 Nicotinic Acetylcholine Receptor Regulates the Function and Viability of L Cells

Enteroendocrine L cells secrete the incretin hormone glucagon-like peptide-1 (GLP-1), and they also express the α7 nicotinic acetylcholine receptor (α7nAChR), which may regulate GLP-1 secretion. Here, GTS-21, a selective α7nAChR agonist, was used to examine the effect of α7nAChR activation in L-cell...

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Bibliografske podrobnosti
izdano v:Endocrinology
Main Authors: Wang, Dawei, Meng, Qinghe, Leech, Colin A, Yepuri, Natesh, Zhang, Linlin, Holz, George G, Wang, Chunting, Cooney, Robert N
Format: Artigo
Jezik:Inglês
Izdano: Endocrine Society 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456923/
https://ncbi.nlm.nih.gov/pubmed/29992246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2018-00433
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