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Glibenclamide ameliorates the disrupted blood–brain barrier in experimental intracerebral hemorrhage by inhibiting the activation of NLRP3 inflammasome

BACKGROUND: Glibenclamide is a widely used sulfonylurea drug prescribed to treat type II diabetes mellitus. Previous studies have demonstrated that glibenclamide has neuroprotective effects in central nervous system injury. However, the exact mechanism by which glibenclamide acts on the blood–brain...

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Detalhes bibliográficos
Publicado no:Brain Behav
Main Authors: Xu, Fulin, Shen, Gang, Su, Zuopeng, He, Zijian, Yuan, Lutao
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456786/
https://ncbi.nlm.nih.gov/pubmed/30859754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/brb3.1254
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