Human Cytomegalovirus Antigen Presentation by HLA-DR+ NKG2C+ Adaptive NK Cells Specifically Activates Polyfunctional Effector Memory CD4+ T Lymphocytes

Natural killer (NK) cells play a dual role in the defense against viral pathogens by directly lysing infected cells as well as by regulating anti-viral T cell immunity. Infection by human cytomegalovirus (HCMV) promotes a persistent expansion of NKG2C+ adaptive NK cells which have been shown to disp...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Costa-García, Marcel, Ataya, Michelle, Moraru, Manuela, Vilches, Carlos, López-Botet, Miguel, Muntasell, Aura
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456717/
https://ncbi.nlm.nih.gov/pubmed/31001281
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00687
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