Multiple Epistasis Interactions Within MHC Are Associated With Ulcerative Colitis

Successful searching for epistasis is much challenging, which generally requires very large sample sizes and/or very dense marker information. We exploited the largest Crohn's disease (CD) dataset (18,000 cases + 34,000 controls) and ulcerative colitis (UC) dataset (14,000 cases + 34,000 contro...

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Bibliographische Detailangaben
Veröffentlicht in:Front Genet
Hauptverfasser: Zhang, Jie, Wei, Zhi, Cardinale, Christopher J., Gusareva, Elena S., Van Steen, Kristel, Sleiman, Patrick, Hakonarson, Hakon
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Genetics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456704/
https://ncbi.nlm.nih.gov/pubmed/31001315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.00257
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