Akt/AS160 Signaling Pathway Inhibition Impairs Infection by Decreasing Rab14-Controlled Sphingolipids Delivery to Chlamydial Inclusions

Chlamydia trachomatis, an obligate intracellular bacterium, intercepts different trafficking pathways of the host cell to acquire essential lipids for its survival and replication, particularly from the Golgi apparatus via a Rab14-mediated transport. Molecular mechanisms underlying how these bacteri...

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Detalhes bibliográficos
Publicado no:Front Microbiol
Main Authors: Capmany, Anahí, Gambarte Tudela, Julián, Alonso Bivou, Mariano, Damiani, María T.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456686/
https://ncbi.nlm.nih.gov/pubmed/31001235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2019.00666
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