Epigenetic and therapeutic implications of dnmt3b in temporomandibular joint osteoarthritis

Temporomandibular joint (TMJ) arthritis causes severe debilitation and has few treatment options. Here, we found a small molecule, DNA methyltransferase 3B (Dnmt3b), as a putative therapeutic target, partially rescued osteoarthritic phenotype. Dnmt3b was detected differentially expressed in cell zon...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Zhou, Yue, Chen, Mo, O’Keefe, Regis J, Shen, Jie, Li, Zhi, Zhou, Jian, Zhou, Xuedong, Mao, Jeremy J
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2019
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456519/
https://ncbi.nlm.nih.gov/pubmed/30972197
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