A platform for generation of chamber specific cardiac tissues and disease modelling

Tissue engineering using cardiomyocytes derived from human pluripotent stem cells holds a promise to revolutionise drug discovery, but only if limitations related to cardiac chamber specification and platform versatility can be overcome. We describe here a scalable tissue cultivation platform that i...

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Publicado en:Cell
Main Authors: Zhao, Yimu, Rafatian, Naimeh, Feric, Nicole T., Cox, Brian, Aschar-Sobbi, Roozbeh, Wang, Erika Yan, Aggarwal, Praful, Zhang, Boyang, Conant, Genevieve, Pahnke, Kacey Aric, Protze, Stephanie, Lee, Jee Hoon, Davenport Huyer, Locke, Jekic, Danica, Wickeler, Anastasia, Naguib, Hani, Keller, Gordon M., Vunjak-Novakovic, Gordana, Broeckel, Ulrich, Backx, Peter H., Radisic, Milica
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6456036/
https://ncbi.nlm.nih.gov/pubmed/30686581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.11.042
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