Impaired cognitive flexibility following NMDAR-GluN2B deletion is associated with altered orbitofrontal-striatal function

A common feature across neuropsychiatric disorders is inability to discontinue an action or thought once it has become detrimental. Reversal learning, a hallmark of executive control, requires plasticity within cortical, striatal and limbic circuits and is highly sensitive to disruption of N-methyl-...

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I publikationen:Neuroscience
Huvudupphovsmän: Marquardt, Kristin, Josey, Megan, Kenton, Johnny A., Cavanagh, James F., Holmes, Andrew, Brigman, Jonathan L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2019
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Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455963/
https://ncbi.nlm.nih.gov/pubmed/30742964
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2019.01.066
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