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Cholinergic Modulation of CA1 Pyramidal Cells via M1 Muscarinic Receptor Activation: A Computational Study at Physiological and Supraphysiological Levels

The hippocampus receives extensive cholinergic modulation from the basal forebrain, which has been shown to have a prominent role in attention, learning, and synaptic plasticity. Disruptions of this modulation have been linked to a variety of neural disorders including Alzheimer’s Disease. Pyramidal...

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Detalhes bibliográficos
Publicado no:Conf Proc IEEE Eng Med Biol Soc
Main Authors: Mergenthal, Adam R., Bouteiller, Jean-Marie C., Berger, Theodore W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455917/
https://ncbi.nlm.nih.gov/pubmed/30440653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1109/EMBC.2018.8512574
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