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S94. MUTATION-INTOLERANT GENES AND MONOGENIC DISEASE GENES IN 145 LOCI OF SCHIZOPHRENIA (SCZ) GWAS ARE LINKED TO THE ISCHEMIA-HYPOXIA RESPONSE

BACKGROUND: We previously hypothesized that candidate genes for schizophrenia (SCZ) respond to ischemia-hypoxia as part of obstetric complications. Hypoxia may alter gene expression levels depending on genetic variants which in turn affect neurodevelopment (Schmidt-Kastner et al., 2012). The challen...

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Detalhes bibliográficos
Publicado no:Schizophr Bull
Main Authors: Schmidt-Kastner, Rainald, Guloksuz, Sinan, Kietzmann, Thomas, van Os, Jim, Rutten, Bart P F
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455520/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/schbul/sbz020.639
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