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Simultaneous inference of phenotype-associated genes and relevant tissues from GWAS data via Bayesian integration of multiple tissue-specific gene networks

Although genome-wide association studies (GWAS) have successfully identified thousands of genomic loci associated with hundreds of complex traits in the past decade, the debate about such problems as missing heritability and weak interpretability has been appealing for effective computational method...

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Bibliographic Details
Published in:J Mol Cell Biol
Main Authors: Wu, Mengmeng, Lin, Zhixiang, Ma, Shining, Chen, Ting, Jiang, Rui, Wong, Wing Hung
Format: Artigo
Language:Inglês
Published: Oxford University Press 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455106/
https://ncbi.nlm.nih.gov/pubmed/29300920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jmcb/mjx059
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