Ultra-small gadolinium oxide nanocrystal sensitization of non-small-cell lung cancer cells toward X-ray irradiation by promoting cytostatic autophagy

BACKGROUND: Gadolinium-based nanoparticles (GdNPs) have been used as theranostic sensitizers in clinical radiotherapy studies; however, the biomechanisms underlying the radio-sensitizing effects of GdNPs have yet to be determined. In this study, ultra-small gadolinium oxide nanocrystals (GONs) were...

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Vydáno v:Int J Nanomedicine
Hlavní autoři: Li, Feifei, Li, Zihou, Jin, Xiaodong, Liu, Yan, Zhang, Pengcheng, Li, Ping, Shen, Zheyu, Wu, Aiguo, Chen, Weiqiang, Li, Qiang
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2019
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455003/
https://ncbi.nlm.nih.gov/pubmed/31040665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S193676
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