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A novel hybrid compound LLP2A-alendronate accelerates open fracture healing in a rabbit model

PURPOSE: LLP2A-alendronate (LLP2A-Ale) is a novel bone-seeking compound that recruits mesenchymal stem cells to the bone surface and stimulates bone formation. The purpose of this study was to investigate the efficacy of LLP2A-Ale in the treatment of rabbit open fracture. METHODS: Thirty New Zealand...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Wang, Zheng, Zhao, Yong, Zhang, Dong, Qi, Baiwen, Xiao, Weidong, Hu, Xiang, Yu, Aixi
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6455002/
https://ncbi.nlm.nih.gov/pubmed/31040645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S195937
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