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A phase 1, open-label, single-arm study evaluating the ocular safety of OTX-101 and systemic absorption of cyclosporine in healthy human volunteers

PURPOSE: To evaluate the ocular safety of OTX-101 0.09% – a novel, nanomicellar, clear, aqueous solution of cyclosporine (CsA) – and to determine the systemic exposure to CsA following ophthalmic administration. PATIENTS AND METHODS: Healthy volunteers ≥18 years of age were recruited for participati...

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מידע ביבליוגרפי
הוצא לאור ב:	Clin Ophthalmol
Main Authors:	Karpecki, Paul M, Weiss, Sidney L, Kramer, William G, O’Connor, Patrick, Evans, David, Johnston, Josh, Jasper, April L, Justice, Angela, Ogundele, Abayomi B, Devries, Doug
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Dove Medical Press 2019
נושאים:	Original Research
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC6454998/ https://ncbi.nlm.nih.gov/pubmed/31040639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OPTH.S187945
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A phase 1, open-label, single-arm study evaluating the ocular safety of OTX-101 and systemic absorption of cyclosporine in healthy human volunteers

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