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The Drosophila Small Conductance Calcium-Activated Potassium Channel Negatively Regulates Nociception

Inhibition of nociceptor activity is important for the prevention of spontaneous pain and hyperalgesia. To identify the critical K(+) channels that regulate nociceptor excitability, we performed a forward genetic screen using a Drosophila larval nociception paradigm. Knockdown of three K(+) channel...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Walcott, Kia C.E., Mauthner, Stephanie E., Tsubouchi, Asako, Robertson, Jessica, Daniel Tracey, W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454897/
https://ncbi.nlm.nih.gov/pubmed/30231996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.070
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