Donor Allospecific CD44(high) Central Memory T Cells Have Decreased Ability to Mediate Graft-vs.-Host Disease

Data from both animal models and humans have demonstrated that effector memory T cells (T(EM)) and central memory T cells (T(CM)) from unprimed donors have decreased ability to induce graft-vs-host disease (GVHD). Allospecific T(EM) from primed donors do not mediate GVHD. However, the potential of a...

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Pubblicato in:Front Immunol
Autori principali: Huang, Wei, Mo, Wenjian, Jiang, Jieling, Chao, Nelson J., Chen, Benny J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454869/
https://ncbi.nlm.nih.gov/pubmed/31001254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00624
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