Bone marrow-derived CXCR4-overexpressing MSCs display increased homing to intestine and ameliorate colitis-associated tumorigenesis in mice

BACKGROUND AND OBJECTIVE: Increasing interest has developed in the therapeutic potential of bone marrow-derived mesenchymal stem cells (MSCs) for the treatment of inflammatory bowel disease (IBD) and IBD-induced cancer. However, whether MSCs have the ability to suppress or promote tumor development...

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Detalhes bibliográficos
Publicado no:Gastroenterol Rep (Oxf)
Main Authors: Zheng, Xiao-Bin, He, Xiao-Wen, Zhang, Long-Juan, Qin, Hua-Bo, Lin, Xu-Tao, Liu, Xuan-Hui, Zhou, Chi, Liu, Hua-Shan, Hu, Tuo, Cheng, Hai-Chun, He, Xiao-Sheng, Wu, Xian-Rui, Chen, Yu-Feng, Ke, Jia, Wu, Xiao-Jian, Lan, Ping
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454852/
https://ncbi.nlm.nih.gov/pubmed/30976426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gastro/goy017
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