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Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance and hyperactive cell cycle signaling involved in hepatocellular carcinoma onset and progression

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading cause of cancer associated deaths worldwide. Independent studies have proposed altered DNA methylation pattern and aberrant microRNA (miRNA) levels leading to abnormal expression of different genes as important regulators of disease on...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Zahid, Kashif Rafiq, Su, Mingyang, Khan, Abdur Rehman Raza, Han, Shiming, Deming, Gou, Raza, Umar
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454777/
https://ncbi.nlm.nih.gov/pubmed/31007607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0804-3
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