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Systems biology based meth-miRNA–mRNA regulatory network identifies metabolic imbalance and hyperactive cell cycle signaling involved in hepatocellular carcinoma onset and progression

BACKGROUND: Hepatocellular carcinoma (HCC) is one of the leading cause of cancer associated deaths worldwide. Independent studies have proposed altered DNA methylation pattern and aberrant microRNA (miRNA) levels leading to abnormal expression of different genes as important regulators of disease on...

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Dades bibliogràfiques
Publicat a:Cancer Cell Int
Autors principals: Zahid, Kashif Rafiq, Su, Mingyang, Khan, Abdur Rehman Raza, Han, Shiming, Deming, Gou, Raza, Umar
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454777/
https://ncbi.nlm.nih.gov/pubmed/31007607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0804-3
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