Implementation of genotype-guided dosing of warfarin with point-of-care genetic testing in three UK clinics: a matched cohort study

BACKGROUND: Warfarin is a widely used oral anticoagulant. Determining the correct dose required to maintain the international normalised ratio (INR) within a therapeutic range can be challenging. In a previous trial, we showed that a dosing algorithm incorporating point-of-care genotyping informatio...

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Udgivet i:BMC Med
Main Authors: Jorgensen, Andrea L., Prince, Clare, Fitzgerald, Gail, Hanson, Anita, Downing, Jennifer, Reynolds, Julia, Zhang, J. Eunice, Alfirevic, Ana, Pirmohamed, Munir
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454722/
https://ncbi.nlm.nih.gov/pubmed/30961588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12916-019-1308-7
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