Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

BACKGROUND: Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. METHODS: Infant (2 weeks old) and adult (6 weeks old) mice were submitted to sepsis by intraper...

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Detalhes bibliográficos
Publicado no:Crit Care
Main Authors: Colón, David F., Wanderley, Carlos W., Franchin, Marcelo, Silva, Camila M., Hiroki, Carlos H., Castanheira, Fernanda V. S., Donate, Paula B., Lopes, Alexandre H., Volpon, Leila C., Kavaguti, Silvia K., Borges, Vanessa F., Speck-Hernandez, Cesar A., Ramalho, Fernando, Carlotti, Ana P., Carmona, Fabio, Alves-Filho, Jose C., Liew, Foo Y., Cunha, Fernando Q.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454713/
https://ncbi.nlm.nih.gov/pubmed/30961634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-019-2407-8
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