A pharmacogenetic study of patients with schizophrenia from West Siberia gets insight into dopaminergic mechanisms of antipsychotic-induced hyperprolactinemia

BACKGROUND: Hyperprolactinemia (HPRL) is a classical side effect of antipsychotic drugs primarily attributed to blockade of dopamine D2 receptors (DRD2s) on the membranes of lactotroph cells within the pituitary gland. Certain antipsychotic drugs, e.g. risperidone, are more likely to induce HPRL bec...

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Publicat a:BMC Med Genet
Autors principals: Osmanova, Diana Z., Freidin, Maxim B., Fedorenko, Olga Yu., Pozhidaev, Ivan V., Boiko, Anastasiia S., Vyalova, Natalia M., Tiguntsev, Vladimir V., Kornetova, Elena G., Loonen, Anton J. M., Semke, Arkadiy V., Wilffert, Bob, Bokhan, Nikolay A., Ivanova, Svetlana A.
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454588/
https://ncbi.nlm.nih.gov/pubmed/30967134
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-019-0773-3
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