Altered Bile Acid Profile in Mild Cognitive Impairment and Alzheimer’s Disease: Relationship to Neuroimaging and CSF Biomarkers

INTRODUCTION: Bile acids (BAs) are the end products of cholesterol metabolism produced by human and gut microbiome co-metabolism. Recent evidence suggests gut microbiota influence pathological features of Alzheimer’s disease (AD) including neuroinflammation and amyloid-β deposition. METHOD: Serum le...

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Pubblicato in:Alzheimers Dement
Autori principali: Nho, Kwangsik, Kueider-Paisley, Alexandra, MahmoudianDehkordi, Siamak, Arnold, Matthias, Risacher, Shannon L., Louie, Gregory, Blach, Colette, Baillie, Rebecca, Han, Xianlin, Kastenmüller, Gabi, Jia, Wei, Xie, Guoxiang, Ahmad, Shahzad, Hankemeier, Thomas, van Duijn, Cornelia M., Trojanowski, John Q., Shaw, Leslie M., Weiner, Michael W., Doraiswamy, P. Murali, Saykin, Andrew J., Kaddurah-Daouk, Rima
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454538/
https://ncbi.nlm.nih.gov/pubmed/30337152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2018.08.012
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