Vaccine display on artificial bacterial spores enhances protective efficacy against Staphylococcus aureus infection

Spores of Bacillus subtilis are encased in a protein coat composed of ∼80 different proteins. Recently, we reconstituted the basement layer of the coat, composed of two structural proteins (SpoVM and SpoIVA) around spore-sized silica beads encased in a lipid bilayer, to create synthetic spore-like p...

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Bibliographic Details
Published in:FEMS Microbiol Lett
Main Authors: Karauzum, Hatice, Updegrove, Taylor B, Kong, Minsuk, Wu, I-Lin, Datta, Sandip K, Ramamurthi, Kumaran S
Format: Artigo
Language:Inglês
Published: Oxford University Press 2018
Subjects:
Research Letter
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454432/
https://ncbi.nlm.nih.gov/pubmed/30084923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/femsle/fny190
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