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Estradiol matrix patches for pubertal induction: stability of cut pieces at different temperatures

OBJECTIVE: Transdermal estradiol patches are primarily designed for adult women. No low-dose patches are licensed for pubertal induction in hypogonadal girls. Low doses can be achieved by cutting a matrix patch into smaller pieces. However, the manufacturers do not guarantee stability or utility of...

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Detalhes bibliográficos
Publicado no:Endocr Connect
Main Authors: Ankarberg-Lindgren, Carina, Gawlik, Aneta, Kriström, Berit, Mazzanti, Laura, Ruijgrok, Elisabeth J, Sas, Theo C J
Formato: Artigo
Idioma:Inglês
Publicado em: Bioscientifica Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454296/
https://ncbi.nlm.nih.gov/pubmed/30851161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/EC-19-0025
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